Mode of action and indication
A complete closure of the glands is not to be achieved by the protein decomposition of course, which cannot be the application goal, because sweating is in its biological function an absolutely vital and existence-securing process. A complete occlusion of the glands would lead to a life-threatening overheating of the organism.
After repeated application of the metal compounds, many sweat sufferers have experienced a significant improvement in the affected skin regions and a reduction in the previously high flow of sweat.
However, a major disadvantage of the application of metal compounds remains the need for continuous application refreshment in order to maintain the success of the treatment, because once blockage and partial occlusion of the sweat gland ducts has been achieved, it is quickly eroded again by the regeneration process of the skin, so that the sweat gland excretory organs are exposed again, with the consequence that the original secretion rate is restored.
The administration of aluminum chloride (AlCl3) is indicated and extremely effective for hyperhidrosis of the armpits (axillaris), hands and feet, with the greatest therapeutic results in the presence of axillaris hyperhidrosis.
In dermatological test series, the external application of metal substances achieved significant improvements in sweat secretion in these skin areas in approximately 90% of test patients suffering from hyperhidrosis axillaris.